Welcome to Add-Aspirin

This website is designed to provide information about the Add-Aspirin Trial, both for people taking part in the trial (participants) and collaborators. Please use the menus at the top of the screen to find out more about the trial.

Add-Aspirin is a large randomised clinical trial, which is taking place in the UK, Republic of Ireland and India. It will recruit 11,000 participants to help find out whether regular aspirin use after treatment for an early stage cancer can prevent the cancer from coming back and preventing deaths.

Congratulations to our top 5 recruiting centres:

  1. Tata Memorial Hospital, Mumbai
  2. University Hospital Coventry & Warwickshire
  3. Worcestershire Royal Hospital
  4. Western General Hospital
  5. Royal Lancaster Infirmary

*FOR GENERAL AND CLINICAL QUERIES, PLEASE CHECK OUR FAQs*

News

Guidance on COVID-19 Vaccination

Please read guidance from our Trial Management Group on having a COVID-19 vaccine whilst participating in Add-Aspirin.

 

ROI Sites: Ransomware attack on HSE IT System
The Add Aspirin sponsor and Cancer Trials Ireland are aware of the impact of the ransomware attack on the HSE IT system and have put the following guidance together for staff at Irish hospitals:
Reporting SAEs: If internet access is still available at your hospital, SAE submissions via Galaxkey should be unaffected. SAEs can also be faxed to the sponsor on the number +44 (0)20 7670 4818.
Access to study documents on the trial website: Please contact the Sponsor (+44(0)20 7670 4892 or +44(0)20 7670 4759) or the Cancer Trials Ireland team (+353 (0)1 6677211) if you require log-in details for the members section of the trial website.
Registrations, randomisations & drug allocation: Registrations & randomisations can continue to be completed via the trial website or by calling +44 (0)20 7670 4925 (Mon – Fri, 09:00-17:00). However, due to the ransomware attack, some hospital staff may not receive emails confirming the registration/randomisation details. However, due to the ransomware attack, some hospital staff may not receive emails confirming the registration/randomisation details. Please call the Add Aspirin sponsor on +44(0)20 7670 4892 or +44(0)20 7670 4759 if you do not have access to your emails.
Unblinding: Sites in ROI who have been affected by the ransomware attack on the HSE IT system can call +44(0)20 7670 4906 out of hours for emergency unblinding. During working hours please email mrcctu.add-aspirin@ucl.ac.uk as normal with any unblinding requests.

If you have any concerns or questions, please call the Cancer Trials Ireland team on +353 (0)1 6677211 or the Sponsor on +44(0)20 7670 4892 or +44(0)20 7670 4759.

Quick Links

Register a participant

From Monday 16th March 2020, to RANDOMISE a participant from the UK please call +44 (0)20 7670 4925, rather than the usual randomisation line.

To RANDOMISE a participant from Republic of Ireland or India only, please use the 'Register a participant' link above to randomise online. Please make sure to press 'Randomise' once logged in to the server.

Unblind a participant in the UK

Unblind a participant in the RoI

Unblind a participant in India

Breast

We aim to recruit 3100 individuals who have had surgery to remove an early stage breast cancer.

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here 

Top recruiters: Tata Memorial Hospital Mumbai, Western General Hospital, Worcestershire Royal Hospital, Churchill Hospital Oxford  

PARTICIPANTS REGISTERED: 4082
PARTICIPANTS RANDOMISED: 3446

Colon/Rectum

We aim to to recruit 2600 individuals who have had surgery to remove an early stage bowel cancer. 

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here 

Top recruiters: Western General Hospital, St James's University Hospital, Bristol Haematology & Oncology Centre, Velindre Hospital

PARTICIPANTS REGISTERED: 2479
PARTICIPANTS RANDOMISED: 2053

Gastro

We aim to recruit 2100 individuals who have had surgery or a combination of chemotherapy and radiotherapy to treat a cancer of the stomach or oesophagus (food pipe).

CURRENT RECRUITMENT STATUS: OPEN

Detailed eligibility criteria available here

Top recruiters: Tata Memorial Hospital Mumbai, Christie Hospital, Cancer Institute (WIA), Basavatarakam Indo-American Cancer Hospital & Research Institute

PARTICIPANTS REGISTERED: 601
PARTICIPANTS RANDOMISED: 479

Prostate

We aim to recruit 2120 individuals who have had surgery or radiotherapy to treat an early stage prostate cancer.

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here

Top recruiters: University Hospital Coventry & Warwickshire, Darent Valley Hospital, University Hospital of Wales, Queen Elizabeth Hospital King's Lynn

PARTICIPANTS REGISTERED: 1953
PARTICIPANTS RANDOMISED: 1677

the trial is being jointly funded by