Welcome to Add-Aspirin

This website is designed to provide information about the Add-Aspirin Trial, both for people taking part in the trial (participants) and collaborators. Please use the menus at the top of the screen to find out more about the trial.

Add-Aspirin is a large randomised clinical trial, which is taking place in the UK, Republic of Ireland and India. It will recruit 11,000 participants to help find out whether regular aspirin use after treatment for an early stage cancer can prevent the cancer from coming back and preventing deaths.

Congratulations to our top 5 recruiting centres:

  1. University Hospitals Coventry & Warwickshire
  2. Tata Memorial Hospital, Mumbai
  3. Worcestershire Royal Hospital
  4. Royal Marsden Hospitals
  5. Queen Elizabeth Hospital, King's Lynn

*FOR GENERAL AND CLINICAL QUERIES, PLEASE CHECK OUR FAQs*

News

New study looking at the risks and benefits of daily aspirin

A number of news outlets recently reported on a new study which has looked at the benefits and risks of taking daily aspirin for individuals without a history of heart disease.

The study pooled data from a number of previous, large clinical trials which have looked at this. The results suggested that aspirin can prevent heart attacks and strokes in these individuals. However, a known but rare side effect of aspirin is internal bleeding. As has been seen in other studies, this research confirmed that those individuals who were taking aspirin in the trials were more likely to suffer serious bleeding, though the risk of bleeding for any individual was small.

Read more

Quick Links

Register a participant

To RANDOMISE a participant from the UK please call +44 (0)20 7670 4777

To RANDOMISE a participant from Republic of Ireland or India only, please use the 'Register a participant' link above to randomise online. Please make sure to press 'Randomise' once logged in to the server.

Unblind a participant in the UK

Unblind a participant in the RoI

Unblind a participant in India

Breast

We aim to recruit 3100 individuals who have had surgery to remove an early stage breast cancer.

CURRENT STATUS:
OPEN 

Detailed eligibility criteria available here 

Top recruiters:  Worcestershire Royal Hospital, Tata Memorial Hospital Mumbai, Western General Hospital, Churchill Hospital Oxford  

PARTICIPANTS REGISTERED: 3219
PARTICIPANTS RANDOMISED: 2645

Colon/Rectum

We aim to to recruit 2600 individuals who have had surgery to remove an early stage bowel cancer. 

CURRENT STATUS:
OPEN 

Detailed eligibility criteria available here 

Top recruiters: Bristol Haematology & Oncology Centre, St James 's University Hospital, Velindre Hospital, Western General Hospital

PARTICIPANTS REGISTERED: 1912
PARTICIPANTS RANDOMISED: 1558

Gastro

We aim to recruit 2100 individuals who have had surgery or a combination of chemotherapy and radiotherapy to treat a cancer of the stomach or oesophagus (food pipe).

CURRENT STATUS:
OPEN 

Detailed eligibility criteria available here

Top recruiters:
Tata Memorial Hospital Mumbai, Christie Hospital, UHCW, Manor Hospital, Churchill Hospital, Oxford

PARTICIPANTS REGISTERED: 395
PARTICIPANTS RANDOMISED: 307

Prostate

We aim to recruit 2120 individuals who have had surgery or radiotherapy to treat an early stage prostate cancer.

CURRENT STATUS:
OPEN 

Detailed eligibility criteria available here

Top recruiters: UCHW,  Darent Valley Hospital, Queen Elizabeth Hospital King's Lynn, University Hospital of Wales

PARTICIPANTS REGISTERED: 1543
PARTICIPANTS RANDOMISED: 1304

the trial is being jointly funded by