Welcome to Add-Aspirin

This website is designed to provide information about the Add-Aspirin Trial, both for people taking part in the trial (participants) and collaborators. Please use the menus at the top of the screen to find out more about the trial.

Add-Aspirin is a large randomised clinical trial, which is taking place in the UK, Republic of Ireland and India. It will recruit 11,000 participants to help find out whether regular aspirin use after treatment for an early stage cancer can prevent the cancer from coming back and preventing deaths.

Congratulations to our top 5 recruiting centres:

  1. University Hospitals Coventry & Warwickshire
  2. Tata Memorial Hospital, Mumbai
  3. Worcestershire Royal Hospital
  4. Royal Marsden Hospitals
  5. Queen Elizabeth Hospital, King's Lynn

*FOR GENERAL AND CLINICAL QUERIES, PLEASE CHECK OUR FAQs*

News

Re-opening Trial Recruitment in the UK and ROI
We’re pleased to announce that we are now in a position to re-open trial recruitment in the UK and ROI in those centres that have the capacity to begin registering patients again. Please refer to the updated guidance found here if your centre is in a position to restart recruitment. 

Congratulations to Kettering General Hospital who have registered the first patient following the suspension to the colorectal cohort.

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Updated guidance on use of NSAIDs and Covid-19

Please read our latest guidance on non-steroidal anti-inflammatory drugs (NSAIDs) and Covid-19 here.

 

Quick Links

Register a participant

From Monday 16th March 2020, to RANDOMISE a participant from the UK please call +44 (0)20 7670 4925, rather than the usual randomisation line.

To RANDOMISE a participant from Republic of Ireland or India only, please use the 'Register a participant' link above to randomise online. Please make sure to press 'Randomise' once logged in to the server.

Unblind a participant in the UK

Unblind a participant in the RoI

Unblind a participant in India

Breast

We aim to recruit 3100 individuals who have had surgery to remove an early stage breast cancer.

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here 

Top recruiters: Tata Memorial Hospital Mumbai, Western General Hospital, Worcestershire Royal Hospital, Churchill Hospital Oxford  

PARTICIPANTS REGISTERED: 3733
PARTICIPANTS RANDOMISED: 3191

Colon/Rectum

We aim to to recruit 2600 individuals who have had surgery to remove an early stage bowel cancer. 

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here 

Top recruiters: St James's University Hospital, Western General Hospital, Bristol Haematology & Oncology Centre, Velindre Hospital

PARTICIPANTS REGISTERED: 2242
PARTICIPANTS RANDOMISED: 1876

Gastro

We aim to recruit 2100 individuals who have had surgery or a combination of chemotherapy and radiotherapy to treat a cancer of the stomach or oesophagus (food pipe).

CURRENT RECRUITMENT STATUS: OPEN

Detailed eligibility criteria available here

Top recruiters: Tata Memorial Hospital Mumbai, Christie Hospital, Cancer Institute (WIA), UHCW, St James's University Hospital

PARTICIPANTS REGISTERED: 490
PARTICIPANTS RANDOMISED: 403

Prostate

We aim to recruit 2120 individuals who have had surgery or radiotherapy to treat an early stage prostate cancer.

CURRENT RECRUITMENT STATUS:
OPEN

Detailed eligibility criteria available here

Top recruiters: UHCW,  Darent Valley Hospital, Queen Elizabeth Hospital King's Lynn, University Hospital of Wales

PARTICIPANTS REGISTERED: 1804
PARTICIPANTS RANDOMISED: 1567

the trial is being jointly funded by